Advanced Knee Pain Relief from Osteoarthritis Without Surgery, Opioids, or Downtime! Since 2018, Arthritis Knee Pain Centers (AKPC) has specialized in FDA-approved, non-surgical treatments for osteoarthritis of the knee. We’ve helped over 60,000 patients find relief from their pain and inflammation and return to the active, joyful lifestyles they love. We have 18 medical practices across the United States. With osteoarthritis the naturally occurring fluid that lubricates your knees is diminished causing, grinding, pain and inflammation. Our specially trained physicians replace that lost fluid with an FDA-approved lubricating, and cushioning gel.