Obertshausen is a town in the Offenbach district in the Regierungsbezirk in the state of Hessen, Germany. It has around 24,000 inhabitants. Obertshausen is one of 13 towns and municipalities in the Offenbach district. The town lies in the thickly wooded eastern part of the Rhine-Main lowland south of the Main and southeast of Frankfurt am Main and Offenbach am Main at an elevation of 112 m above sea level. Southwest of the town is found Darmstadt, the seat of the like-named Regierungsbezirk. To the northeast lies the town of Hanau. Obertshausen lies in the southern part of Hesse, not far from the Odenwald and the Spessart.