Pythagoreio is a town and municipal unit on the island of Samos, North Aegean, Greece. Before the 2011 local government reform, Pythagoreio was a municipality. Since 2019, it is a municipal unit of East Samos. In 2021, the town's population was 7,515. It is the largest municipal unit in land area on Samos, at 164.662 km². It shares the island with the mu…Pythagoreio is a town and municipal unit on the island of Samos, North Aegean, Greece. Before the 2011 local government reform, Pythagoreio was a municipality. Since 2019, it is a municipal unit of East Samos. In 2021, the town's population was 7,515. It is the largest municipal unit in land area on Samos, at 164.662 km². It shares the island with the municipal units of Vathy, Karlovasi, and Marathokampos. The archaeological remains in the town, known collectively as Pythagoreion, has designated a joint UNESCO World Heritage Site with nearby Heraion.