Ribosomal RNA (rRNA) molecules were initially characterized ... type of rRNA gene that encodes three distinct RNA species: the 23S, 5S, and 16S rRNAs. In comparison, eukaryotic cells contain ...

Now, for the first time, double stranded RNA helices and the α-helices of ribosomal proteins are readily ... SRL and the 1070 and 1100 helices in of 23S rRNA) were fit into the electron density ...

Large Subunit rRNAs: The large subunit in prokaryotes contains the 23S and 5S rRNAs, while in eukaryotes ... The rRNA structures also provide binding sites for ribosomal proteins, which help stabilize ...

Macrolides bind reversibly to 23S ribosomal RNA (rRNA) of the 50S subunit of bacterial ribosome inhibiting RNA-dependent protein synthesis. Clindamycin (a lincosamide) at subgrowth inhibitory ...