Multiple causes of metabolic acidosis exist, including increased acid production or ingestion (e.g., aspirin toxicity), ...

Excess acid production or kidney failure causes metabolic acidosis. Lung dysfunction or disease causes respiratory acidosis.

Kidney disease that becomes progressively worse is ... and shortness of breath. Metabolic acidosis is when acid builds up in your body because your kidneys are not functioning properly.

Individuals with metabolic acidosis may require bicarbonate supplements ... the risk of heart disease and stroke. Chronic kidney disease makes it difficult for the kidneys to function properly ...

Renal tubular acidosis causes include Addison’s disease, drugs, mineralcorticoid deficiency.