Apoptosis and autophagy constitute the two self-destructive processes by which supernumerary, damaged or aged cells and organelles are eliminated. Beyond this homeostatic function, autophagy is ...

In multicellular organisms, the total number of cells is a balance between the cell-generating effects of mitosis and cell death that is induced through apoptosis. A disruption of this delicate ...

Decades ago, scientists utilized living cells to discover that pancratistatin triggers apoptosis in cancerous testicular, breast, liver and nerve cells. Since then, researchers have relied on ...

Unlike other forms of cell death, necroptosis shares features of both apoptosis (natural cell breakdown ... In an in vitro model mimicking optic nerve damage, RGCs exposed to oxygen-glucose ...

Glaucoma is a complex and multifactorial neurodegenerative disorder primarily characterized by the progressive loss of retinal ganglion cells (RGCs) and their axons, leading to irreversible visual ...