whereas the inhibition of autophagy can sensitize cancer cells to chemotherapy to promote p53-induced apoptosis. Thus, manipulation of autophagy can determine cell-fate decisions in clinical settings.

A research team affiliated with UNIST has unveiled an innovative technology to eliminate drug-resistant cancer cells using ...

Liver Health: Autophagy may prevent damage caused to the liver by alcohol, drugs, or conditions known as fatty liver. Cancer: While autophagy may inhibit early tumor growth by removing damaged ...

A new study unravels the relationship between mitofusins (mitochondrial proteins) and autophagy. Using gene editing with CRISPR-Cas9, the team has been able to study these proteins without altering ...

Our cells constantly receive DNA damage from factors such as ultraviolet rays, irradiations, toxins and chemicals. For women, ...

Abstract Autophagy is a crucial quality control mechanism that degrades damaged cellular components through lysosomal fusion with autophagosomes ...

Melanoma is one of the most aggressive skin cancers, with over 300,000 new cases reported worldwide each year. In Europe, the number of diagnoses has been rising rapidly.

Impaired autophagy is linked to cardiovascular diseases, neurodegenerative diseases like Alzheimer's disease and Parkinson's disease, and metabolic disorders like diabetes and cancer. Various ...

Our cells constantly receive DNA damage from factors such as ultraviolet rays, irradiations, toxins and chemicals.