Guan's lab has focused on how autophagy, or the cell's "recycling" function, affects cancer metastasis. "Autophagy can be ...

View Full Profile. Learn about our Editorial Policies. Guan and his team compared 171 genes that influence autophagy to study how they affect metastasis in a mouse model of breast cancer. By using ...

The study also raises the possibility of exploring the autophagy-ferroptosis axis ... therapies to address this critical aspect of cancer metastasis. More information: Yewei Jia et al, Melanoma ...

Every cell in the body normally has its fixed place as part of a tissue structure. Except for a few cell types, such as blood ...

Impaired autophagy is linked to cardiovascular diseases, neurodegenerative diseases like Alzheimer's disease and Parkinson's disease, metabolic disorders like diabetes and cancer. Various proteins ...