Core clock genes interact with DNA damage response pathways, modulating the activity of key proteins like ATM and ATR, while BHLHE40 and CCAR2 serve as critical hubs connecting aging, circadian ...

such as blood counts and biochemical tests, to assess physiological aging. However, these markers do not accurately reflect specific metabolic or physiological pathways that contribute to aging.

The most comprehensive model of the brain’s metabolism, incorporating more than 16,800 biochemical interactions ... could help restore metabolic function in aging brains. Potentially, these ...

The pathway contributes to healthy aging in this way." By learning more about the biochemical processes that activate this protein, the team hopes to offer new insights for future therapeutics ...

While numerous studies explore its biochemical properties ... The search for compounds that might impact cellular aging ...