CD163 might not be the most exciting name in the world, but behind it lies one of the body's most important defense receptors ...

Platelets have a broad repertoire of receptor molecules that enable them to sense invading pathogens and infection-induced inflammation. Consequently, platelets exert antimicrobial effector ...

A drug developed as an antidote to the antiplatelet agent ticagrelor safely and effectively reversed ticagrelor's ...

Until recently, researchers believed that platelet spreading and clot contraction were controlled by the same pathway. However a recent study from Thomas Jefferson University researchers challenges ...

Platelet activation and blood clot formation can sometimes be ... acts on a specific platelet component called the pregnane X receptor to have its effect on platelet activation.

They showed that plasma or whole blood from individuals ... the effect of autoantibodies on platelet production. Binding of TPO to the megakaryocyte receptor c-Mpl improves megakaryocyte survival ...

"I couldn't fathom being able to do it." He laughs about that now as he sits in a chair-for two hours-donating platelets at the Kraft Family Blood Donor Center. Within days, patients at Dana ...

New research reveals how intermittent fasting alters gut bacteria to boost levels of a key metabolite, reducing the risk of deadly blood clots and heart attacks. Could fasting be the key to a ...

Activation of platelets is triggered by direct adhesion of the parasites to platelet receptors, in addition to other stimuli, such as increased levels of CRP. After contact with parasites ...

When skin is cut or damaged, tiny cell fragments circulating in the blood, called platelets, arrive at the injury and spread ...