Recent studies are, however, illustrating that three different mechanisms of airflow obstruction play a role in COPD pathogenesis. The first is the loss of support of the small airways in ...

Over the past years, many details of the molecular pathogenesis of COPD have been revealed. This has offered new points of possible interventions, many of which are currently under investigation.

Besides metabolic disorders, microorganisms and their metabolites also play a key role in COPD pathogenesis. Individuals with COPD are prone to microbial colonization in their lower respiratory tract.

In conclusion, Tim-3 was characterized as a novel immune checkpoint molecule with pathophysiological significance in respiratory oncology. Its stage-dependent expression dynamics and multimodal ...

Researchers from Shanghai Jiao Tong University and affiliated organizations have published their findings from studies that aimed to investigate the pathogenesis of idiopathic pulmonary fibrosis (IPF) ...