No doubt 2025 will usher in many more advances in CRISPR therapies, thanks to the FDA’s new Platform Technology Designation ...

A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...

Biomedical engineers at Duke University have demonstrated a promising new approach that could be used to treat a rare and ...

The standard Cas9 protein cuts the DNA at the target. When the cut is repaired, mutations are introduced that usually disable a gene. This is by far the most common use of CRISPR. It’s called ...

No babies have been born with changes made by CRISPR/Cas9 or any other gene-editing technology. But it could be only a matter of time. “I would not be surprised if there were a CRISPR-modified ...

CRISPR technology has radically transformed genetic research, and at the forefront of this transformation is CRISPR screening ...

“RNAi allows for reversible gene silencing, unlike most applications of CRISPR/Cas9 where edits to the genome are permanent,” says Lin. Plus, there are ways to mediate off-target effects using ...

Researchers using CRISPR-Cas9 gene editing tools have discovered that while this technology can enhance T cell cancer therapies, it may also lead to unintended chromosomal loss in the edited immune ...

Akribion Therapeutics emerges from stealth with €8 million in seed funding to develop a novel cancer RNA-guided approach ...

To create a CRISPR gene drive, scientists engineer an organism’s DNA to contain the desired gene along with genes coding for guide RNA and Cas9 molecular scissors. When the edited organism mates with ...

CRISPR Therapeutics is a leading gene editing company focused on developing CRISPR/Cas9-based therapeutics ... a superoxide dismutase 1, or SOD1, silencing gene therapy for amyotrophic lateral ...

which engages in the development of transformative gene-based medicines for serious diseases using its proprietary CRISPR/Cas9 platform. Its CRISPR/Cas9 platform is a gene editing technology that ...