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CTLA4免疫疗法，和它带来的“超级幸存者”因此，机体进化出了一些“刹车机制”，来平衡免疫系统，防止它使出“洪荒之力”。 CTLA4和PD1，这俩存在于免疫细胞上的蛋白，就是这样的“刹车 ...
Interestingly, CTLA-4 knockout mice and mice that lack expression of CTLA-4 just in T REG develop fatal, early-onset lymphoproliferative disease. 1,4 In addition, expression and signaling of CTLA ...
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