The interplay between aging and cellular senescence reveals insights into chronic inflammation and potential strategies for ...

Cellular senescence, the permanent state of cell-cycle arrest, is emerging as an intrinsic barrier against tumorigenesis and a mechanism contributing to organismal ageing. Unexpected findings now ...

Despite its prevalence, the exact mechanisms driving MASLD remain unclear, limiting the development of effective treatments.

Cellular senescence is an irreversible cell-cycle arrest that can be triggered in response to several stimuli, including the shortening of telomeres. It has long been thought to represent a tumour ...

A team led by Prof. Wuran Wei from West China Hospital of Sichuan University and Dr. Dechao Feng from the Division of Surgery ...

At this point, DNA repair systems recognize it as DNA damage and trigger a form of permanent cell cycle arrest called replicative senescence, which may lead to cell death called apoptosis. 5 This ...

Proteins that trigger cell senescence occupy much of the literature on aging, but a small RNA moves into the limelight. Kamal is a freelance science journalist based in the UK with a PhD in virology ...

Specifically, neurons in the hippocampus and cortex exhibited markers of senescence, including the expression of p16, a ...