The cytoskeleton of eukaryotic cells is ... strength and support for the fragile tubulin structures. All cells have intermediate filaments, but the protein subunits of these structures vary.

intermediate filaments, and microtubules. Each of these helps maintain cell structure and function throughout interphase and is essential as the cell progresses through the cell cycle. To support ...

Actin proteins group together to form a network of thin filaments that spread throughout a cell. This actin network is dynamic, meaning that the filaments can either grow or shrink to fit the ...

[1] The eukaryotic cell cytoskeleton consists of three distinct species of filamentous structures: microfilaments, intermediate filaments and microtubules, composed mainly of actin, vimentin ...

Integrins link the actin cytoskeleton of a cell to various external structures ... and other adaptor complexes bind desmosomes to intermediate filaments. Both of these types of junctional ...

Changes to the intermediate filament (IF) protein, vimentin, were found to promote tumor growth by increasing cancer stemness in an oestrogen independent manner.

Approximately 15% of the proteins produced in our bodies are destined for the surface of our cells. Remarkably ... to elucidate the interplay of clathrin structures with the actin cytoskeleton and ...

Myosin II plays the most important role in cellular force generation. Myosin II molecules self-assemble into filaments with different structures depending on myosin II isoforms and other conditions ...

We aim to understand the molecular logic behind the dynamics of the actin cytoskeleton at endocytic sites and how disturbances in this process affect physiology and disease progression. Leonardo is ...

The cytoskeleton is involved in all main functions of immune cells related to the response to infection. Studies of the cytoskeletal proteome can vastly contribute to our understanding of ...