The cysteine protease family called caspases is composed of both initiators and effectors, have crucial roles in cell death and drive mechanistically ... of a multiprotein complex, termed the ...

In Ming-Chiu Fung’s immunology lab, Hogan had been investigating how disturbances in the cytoskeletons of cells might contribute to the fragmentation of mitochondria during apoptosis, the most ...

Protein complexes within each cell ... an important role in the balance between cell growth and death. Although it sounds like a bad thing, apoptosis — or the process of programmed cell death ...

Human α–lactalbumin made lethal to tumor cells (HAMLET) is the first member in a new family of protein–lipid complexes that ... of specific steps in tumor cell death. HAMLET is broadly ...

Cuproptosis is a unique, copper-dependent form of cell death that differs from apoptosis and necrosis. It occurs when intracellular copper binds to proteins involved in the tricarboxylic acid (TCA ...