Discover the latest breakthroughs in migraine treatment for 2025, including CGRP inhibitors, AI-powered personalized plans, ...

The American College of Physicians strongly recommends adding a triptan to an NSAID to treat adults with moderate to severe ...

The following is a summary of “Effectiveness and safety of anti-CGRP monoclonal antibodies for migraine in patients over 65 ...

One chemical that may be involved in migraine episode pain is calcitonin gene-related peptide (CGRP). The trigeminal nerve produces large amounts of CGRP in response to pain signals, which may ...

Goadsby’s work showed that CGRP is a key factor in sensitizing these nociceptors. Clinical trials of drugs that block the peptide in people with migraine proved effective both in alleviating ...

Migraine disrupts daily life with invisible neurological pain, causing physical, emotional, and cognitive struggles that go ...

Atogepant vs placebo for the preventative treatment of migraine alleviated migraine symptoms across 3 clinical trials on day 1.

"Plasma Calcitonin Gene-Related Peptide (CGRP) is one of the main neuropeptides involved in migraine pathophysiology and the levels return to normal once the headache subsides. The other chemicals ...

Pfizer’s Vydura has become the first oral CGRP antagonist recommended for routine use by the NHS to prevent episodic migraine attacks, after being rejected earlier this year as an acute treatment.

Findings showed meloxicam/rizatriptan statistically significantly improved migraine treatment response compared with prior oral CGRP inhibitor treatment. Topline data were announced from a phase 3 ...

47.9% of patients reported sustained pain relief for 24 hours with Symbravo, compared to 16.7% with oral CGRP inhibitors. In the trial, Symbravo rapidly and substantially improved migraine pain ...