and breed with the homozygous floxed mouse (B). The resulting experimental mouse is hemizygous for Cre and homozygous for loxP (D). This is the necessary genotype required to conditionally knock out ...

With the introduction of sequence-specific recombination systems such as FLP/FRT or Cre/LoxP, not only can one dramatically increase the efficiency of generating mosaic animals, but also control ...

All our multiexpression systems (currently MultiBac, MultiMam and MultiColi) rely on in vitro Cre-loxP recombination of Acceptor and Donor plasmids to assemble multiprotein expression vectors. A ...