2 The team next wanted to test these findings in a physiological context; they were curious to see how negative supercoiling, or under twisting of DNA that happens during normal transcription and ...

CRISPR places an entirely new kind of power into human hands. For the first time, scientists can quickly and precisely alter, delete, and rearrange the DNA of ... The black-footed ferret is ...

Collaborative research led by investigators at Dana-Farber/Boston Children's Cancer and Blood Disorders Center defines a novel approach to understanding how certain proteins called transcription ...

Washington: A revolution is underway in gene editing-- and at its forefront is David Liu, an American molecular biologist whose pioneering work is rewriting the building blocks of life with ...

The essence of CRISPR is simple: it’s a way of finding a specific bit of DNA inside a cell. After that, the next step in CRISPR gene editing is usually to alter that piece of DNA. However ...

This is done without the need for nucleic acid amplification. In CRISPR/Cas-based diagnostic tests, guide RNAs bind pathogen DNA or RNA, triggering Cas enzymes to become active and cleave the ...

a variant of the type I-E CRISPR-Cas system, providing insights into its DNA recognition and cleavage mechanisms. The study, published in Nature Communications, was conducted by researchers from ...

The CRISPR-Cascade assay achieves attomolar sensitivity and incorporates an OR-gated logic function to identify multiple pathogens simultaneously through DNA from pathogens associated with ...