Activator proteins bind to regulatory sites on DNA nearby to promoter regions that act as on/off switches. This binding facilitates RNA polymerase activity and transcription of nearby genes.

This active repressor can bind to a region near the promoter called an operator (yellow ... In multicellular organisms, nearly all cells have the same DNA, but different cell types express ...

For instance, the researchers concentrated on a gene called Nanog, which is located on chromosome 6 and is 770,000 bases long. It has three enhancer regions and a promoter, and it is known to ...

Researchers at the University of Tsukuba have developed a vector that integrates the Cre enzyme gene with the specific DNA sequence loxP, which is its target. This vector allows the creation of ...

Large consortia-led projects such as ENCODE (Encyclopedia of DNA Elements) have made great strides in identifying various functional elements of the genome. These include enhancers, activators, and ...