Cells use a variety of programmed cell death mechanisms to maintain homeostasis through cellular self-destruction, including apoptosis, necroptosis, and pyroptosis. A series of rodent experiments ...

This binding inhibits CTSB's protease activity towards BH3-interacting domain death agonist (BID) and receptor-interacting ... CTSB interface promotes host apoptosis while suppressing necroptosis ...

Every day, billions of our cells die and new, healthy ones take their place. In a healthy gut lining, as in most tissues, a type of cell death called apoptosis is thought to mediate this process ...