Scientists found a compound that appears to counter common mutations behind POLG-related diseases, rare conditions that harm ...

Mitochondrial diseases caused by POLG mutations vary in severity. In young children, these diseases can quickly result in brain damage and life-threatening liver problems while others suffer ...

A newly discovered compound appears to counter common mutations behind POLG-related diseases, rare conditions that harm ...

Mitochondrial diseases affect approximately 1 in 5,000 people worldwide, causing debilitating symptoms ranging from muscle ...

New mechanisms discovered that show how development-dependent disruptions in mitochondrial function lead to premature skeletal aging.

In the past, most studies focused on two main ideas about what triggers Alzheimer’s. One idea is that a sticky protein called ...

Researchers have developed a new precision tool for manipulating mitochondrial DNA. The method shows potential for improving ...

Get Instant Summarized Text (Gist) A molecule named PZL-A has been identified as a potential treatment for mitochondrial diseases caused by POLG mutations, which disrupt cellular energy production ...

In the brain, stressed cells can cause neurodegeneration ... the development of Parkinson’s disease and possibly new therapeutic drug targets. Reference: Yamada T, Ikeda A, Murata D, et al. Dual ...

A recent study reveals that dimethyl fumarate (DMF), a compound already approved for other inflammatory diseases, can prevent ...

A medical breakthrough could result in the first treatment for rare but serious diseases in which genetic defects disrupt ...