This historical perspective integrates 50 years of research on SOS mutagenesis in Escherichia coli with the proverbial ... recombination—that feature DNA polymerase V. Genetic and biochemical ...

They were particularly drawn to features of T7 DNA polymerase—derived from the T7 bacteriophage that infects Escherichia coli—due to its ability to synthesize long stretches of DNA by binding and ...

E. coli bacteria could be used to create biodegradable ... It is well known that organisms can naturally synthesize polymers, such as DNA, RNA, cellulose and proteins. However, scientists have ...

to the DNA, and activates an SOS response in the bacterium," says Bergum, from the Department of Clinical and Molecular ...

More information: Sofya K Garushyants et al, Mutational Signatures in Wild Type Escherichia coli Strains Reveal Predominance ...

Biology lectures teach students that when a cell’s replication machinery comes together, DNA polymerase takes off down the double-helix like a car on a highway ...

This information can yield potentially new insights into sequence context effects on polymerase ... characteristics of DNA to generate new protein-binding ligands (see, e.g., ref.