The classic manometric findings are (1) absence of esophageal peristalsis and (2) a hypertensive LES that fails to relax appropriately in response to swallowing. Ambulatory pH monitoring should ...

There is no reliable treatment for ineffective esophageal motility (IEM), a disorder caused by failed smooth-muscle contraction that is common in patients with gastroesophageal reflux disease.

Harder to move stomach juices out of the esophagus. This happens because the squeezing motion of the esophagus (peristalsis) does not work as well as it should. Raynaud's phenomenon is a condition in ...

With primary peristalsis, note that the delay in onset of depolarization, spike burst, and esophageal contraction in the distal esophagus relates to a marked secondary hyperpolarization (arrow).

Delayed esophageal transit on scintigraphy among patients with SSc is linked to a more severe disease phenotype.

"Esophageal motility diagnoses are made based on a global impression that incorporates a patient's symptoms, the endoscopic findings and the motility findings," said Dustin Carlson, MD ...

Peristalsis describes the involuntary wave of muscle contractions that happen naturally in your digestive tract. This automatic bodily function physically moves food and drink through your body ...

Achalasia, a chronic oesophageal motility disorder, is defined by impaired lower oesophageal sphincter relaxation and absent peristalsis, leading to symptoms such as dysphagia and regurgitation.

Researchers discovered that PIEZO1, a pressure-sensitive protein, regulates gut motility and immune responses. In mice, ...