Apoptosis is a highly regulated and critical homeostatic process in multicellular organisms. Aberrations in this form of programmed cell death have been implicated in several pathological conditions ...

Selective modulation of the apoptotic machinery has been the goal of oncology developers for more than two decades. The field continues to face special challenges. Many of the targets are ...

The immune response can also be evaded by inhibiting extrinsic apoptotic signalling ... induced disease and suggest that apoptosis and apoptotic signalling pathways may provide novel targets ...