Researchers have uncovered mechanisms by which mobile genetic elements integrate into the chromosomes of bacteria with linear genomes.
For one, inserting at the end of the chromosome helps the transposon avoid genes for the cell's core functioning, which reside in the middle of the chromosomes; transposons that can target the ...
The team was able to reach protein yields at the pool stage that couldn’t be achieved previously with a random integration approach.
Exploiting transposon ends with appended sequences ... The current library preparation methods for next-generation sequencing are time-consuming and prone to considerable sample loss.
Exploiting transposon ends with appended sequences ... The current library preparation methods for next-generation sequencing are time-consuming and prone to considerable sample loss.