Discover how the brain's most abundant neurotransmitter, glutamate, is revolutionizing psychiatry and offering new hope for ...

the majority of which are ‘glutamatergic’. This means that the presynaptic neuron releases the neurotransmitter glutamate, which crosses the synaptic gap to bind to receptors — usually ...

Homer1a, however, is an endogenous, short, splice variant that lacks the ability to link glutamate receptors to synaptic proteins, and thus competitively dissociates synaptic glutamatergic ...

Although compounds with a combined cholinergic–glutamatergic action have been trialed, none has yet been successful in the later stages of development (Table 4). Consequently, combination ...

A new study in Engineering explores the role of astrocytic G protein-coupled receptors in drug addiction. It shows that these receptors, including ...

The group focuses on studying the mechanisms guiding activity-dependent development of glutamatergic circuitry in the limbic system and in particular, the roles of ionotropic glutamate receptors in ...