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gold, and leflunomide). The suggested mechanisms are mainly based on the results of in vitro laboratory studies and theories about the emergence of DMARD resistance in RA. We also discuss ...

Conventional DMARDs are used as monotherapy or in combination and include methotrexate, leflunomide, azathioprine, ciclosporin, hydroxychloroquine, sulfasalazine, gold and minocycline. Biologic ...