also known as transmembrane receptor guanylyl cyclase A (GC-A). GC-A is a type of single-pass transmembrane receptor protein that spans the cell membrane, connecting a binding region on the cell ...

One key pathway is the soluble guanylyl cyclase–cyclic GMP–protein kinase G system. If it is produced in excess, or if a cell is under conditions of oxidative stress, NO becomes noxious and ma ...

NO SIGNALING:© 2003 Annual ReviewsAll images redrawn from D. Boehning, S.H. Snyder, Ann Rev Neurosci, 26:105–31, 2003.Neuronal nitric oxide synthase (nNOS) is localized to NMDA receptors by the ...