HMG-CoA reductase inhibitors, commonly referred to as statins, are the cornerstone of pharmacologic reduction of elevated low-density lipoprotein cholesterol. LDL-C is the main contributor to ...

In patients with hypercholesterolemia, ezetimibe added to ongoing HMG-CoA reductase inhibitor therapy significantly lowered total cholesterol, LDL-C, apolipoprotein B, and triglycerides and ...

Abstract and Introduction Pathophysiology and Implications of Atherosclerosis Emerging Role of Statins Discussion References Current studies have questioned the relationship between CRP and LDL ...

HMG-CoA reductase inhibitors, better known as statins, are medications taken to lower cholesterol levels. Examples of statins include Lipitor (atorvastatin), lovastatin, and Zocor (simvastatin).

HMG-CoA reductase inhibitors may impair the biosynthesis ot nonsterol isoprenes in a fashion analogous to that observed in mevalonic aciduria ...

aldosterone antagonists and HMG-CoA reductase inhibitors. Early antithrombotic administration at the time of STEMI diagnosis consists of non-enteric-coated aspirin 162 mg to 325 mg (unless ...

They work by inhibiting an enzyme in the liver called HMG-CoA reductase and by inhibiting ... that same effect of causing liver damage. PCSK9 inhibitors are a new class of medications that may ...

Concomitant cisapride, pimozide, ergots, lomitapide, HMG-CoA reductase inhibitors extensively metabolized by CYP3A4 (lovastatin or simvastatin). Concomitant colchicine (in renal or hepatic ...

These medications work by inhibiting an enzyme called HMG-CoA reductase ... managing heart disease and improving heart function. ACE inhibitors (Angiotensin-Converting Enzyme inhibitors) have ...