Researchers identify Lhx2 as key gene in hepatic stellate cells regulating liver regeneration and fibrosis
A research team has identified the transcription factor Lhx2 (LIM homeobox protein 2) as a key regulator in hepatic stellate cells. Lhx2 was found to simultaneously promote liver regeneration and ...
Medscape4d
Hepatic Fibrosis -- Role of Hepatic Stellate Cell Activation
As noted above, stellate cell activation is the central event in hepatic fibrosis. Activation consists of 2 major phases: (1) initiation (also called apreinflammatory stage) and (2) perpetuation ...
Exploring mechanisms of epigenetic regulation in fibrogenic activation of hepatic stellate cells in liver disease
Inflammation and cell death are key triggers of hepatic fibrogenesis in NAFLD, with hepatic stellate cells (HSCs) playing a ...
CytoDyn Announces Findings of Statistically Significant Fibrosis Reversal Across Studies with SMC Laboratories
VANCOUVER, Washington, Feb. 06, 2025 (GLOBE NEWSWIRE) -- CytoDyn Inc. (OTCQB: CYDY) ("CytoDyn" or the "Company"), a biotechnology company developing leronlimab, a CCR5 antagonist with the potential ...
Saint Louis University6mon
Ratna B. Ray, Ph.D.
2017 Exosome mediated intercellular communication between hepatitis C virus infected hepatocytes and hepatic stellate cells. J Virol. 91(6). pii: e02225-16. PMCID: PMC28077652 Sasaki R, Devhare PB, ...
Medscape4d
Hepatic Fibrosis -- Role of Hepatic Stellate Cell Activation
Activation of hepatic stellate cells is the central event in hepatic fibrosis. These perisinusoidal cells orchestrate an array of changes including degradation of the normal ECM of liver ...
CytoDyn Inc.: CytoDyn Announces Findings of Statistically Significant Fibrosis Reversal Across Studies with SMC Laboratories
CytoDyn Inc. (OTCQB: CYDY) ("CytoDyn" or the "Company"), a biotechnology company developing leronlimab, a CCR5 antagonist with the potential for ...