New research highlights how elevated levels of the iron-regulating hormone hepcidin contribute to psoriasis by driving skin cell proliferation and inflammation, offering fresh avenues for therapy.

Hereditary hemochromatosis is an inherited iron overload disorder caused by inappropriately low hepcidin secretion leading to increased duodenal absorption of dietary iron, most commonly in C282Y ...

However, research published in the journal Nature Communications suggests that a hormone called hepcidin could be the cause ...

This candidate is in-licensed from AbbVie (ABBV). HJV provides a critical function in iron metabolism and is required for hepcidin production. DISC-0974 is designed to suppress the production of ...

Proinflammatory cytokines antagonize the action of EPO by exerting an inhibitory effect on erythroid progenitor cells and by disrupting iron metabolism (a process in which hepcidin has a central ...