Early treatment with intravenous bisphosphonates at first radiographic evidence of bone lesions in patients with solid tumors or evidence of osteopenia in patients with multiple myeloma can ...

A study that evaluated the natural history of bisphosphonate-related osteonecrosis of the jaw (ONJ)—an emergent problem for certain patients with cancer—found that reinitiation of ...

IV hydration is not typically necessary; however, patients should be encouraged to drink 2 glasses of water before bisphosphonate infusion. A physician should be consulted prior to administering ...