Thus, neuronal insulin-like signaling appears to be a key regulator of various essential functions in C. elegans, and the metabolic and reproductive defects induced by whole-body deletion of DAF-2 ...

The hormone adrenomedullin disrupts insulin signaling in blood vessel cells, contributing to systemic insulin resistance in obesity-associated type 2 diabetes, according to a new study.

One possibility is that in an attempt to overcome the inhibition within the metabolic insulin-signaling pathway, hyperinsulinemia may continue to stimulate the mitogenic insulin-signaling pathway ...

Insulin is a vital hormone that controls ... such as in the so-called mTOR signaling pathway—a key regulator of cell division ...

Type 2 diabetes mellitus (T2DM) is a complex disorder that has a heterogeneous genetic and environmental background. In this Review, we discuss the role of relatively infrequent polymorphisms of ...

Inositol supplements show significant benefits for hormonal disorders, insulin sensitivity, and fertility issues, offering a ...

Type 2 diabetes mellitus (T2DM) is a prevalent yet complex metabolic disorder that has shown a rising incidence over the past few decades. Recent research has identified flavonoids as compounds ...