If insulin can’t get out of blood vessels, it can’t act in its target tissues. “Endothelial cells are full of insulin ...

Impaired insulin sensitivity, also called insulin resistance, is when cells in your muscles, fat, and liver don’t respond to insulin the way they should. Insulin helps glucose in your blood ...

Figure 1: Molecular mechanisms of cellular insulin resistance in muscle and liver. Figure 2: Mechanisms for intracellular diacylglycerol (DAG) accumulation in muscle and liver. Given the crucial ...

Regardless of the cell type, the researchers found that damage to the mitochondria did not cause cell death. This observation ...

Insulin encourages the storage of excess glucose as glycogen in the liver and muscles. It also promotes fat storage in adipose tissue, which can be used as energy whenever your body needs it.

Researchers investigate the underlying mechanisms of endothelial insulin resistance involved in obesity-associated diabetes.

Type 2 diabetes is a condition where the body cannot produce enough insulin or does not use insulin effectively. Insulin is a ...

The hormone adrenomedullin disrupts insulin signaling in blood vessel cells, contributing to systemic insulin resistance in obesity-associated type 2 diabetes, according to a new study.

Diabetes cases are surging in India and experts are now wondering if traditional Indian diet habits ad modern lifestyle have ...

Adrenomedullin disrupts insulin signaling in blood vessels, leading to systemic insulin resistance in obesity-associated type 2 diabetes.