“We know of about 40 genes that play a role in polycystic kidney disease. But these genes have yet to explain the trigger of ...

This eBook provides insight into the science behind aProximate ™, an innovative proximal tubule cell model designed to mimic human kidney function with exceptional accuracy. It will also look at ...

As a result, the excess glucose shows up in the urine. Some common conditions that cause hyperglycemia include: The kidney ...

Many of the epithelial cells of the remaining uninvolved but dilated tubules contained clear vacuoles that did not stain for fat. Figure 3 Photomicrograph of Kidney in Case 1, Showing Urate ...

Thus, when the blood flow to the kidney is affected, it can result in damage to the kidney tubules, which in turn results in increased serum creatinine levels. Other mechanisms which cause renal ...

An alternative approach, to which we subscribe, involves finding a limited number of biomarkers that identify injury to primary sites in the kidney, such as the glomerulus or the proximal tubule ...

is a progressive disease characterized by damage to the glomerular filtration barrier (GFB), the loss of larger and essential proteins from the blood into the urine (proteinuria), causing considerable ...

Their efforts ultimately succeeded in identifying a combination of cells able to form kidney tubules and Bowman’s capsule in vitro. The cell mix included kidney progenitors with distinct ...

even in advanced chronic kidney disease; cysts derived from proximal tubules, but not those derived from distal tubules, contained increased concentrations of bioactive erythropoietin.

continue along the nephron tubule to the collecting ducts as urine. This eventually passes down to the bladder. In carrying out these processes, the kidney is able to fulfil its functions of ...

Many patients had symptoms and test results suggesting Fanconi syndrome, a condition caused by damage to the renal tubules in the kidneys. Nearly 20 percent were receiving treatment with steroid ...