The study is also a genetic test of the 'mGluR theory' of FXS, which postulates that an important consequence of FXS is excessive signaling through group 1 metabotropic glutamate receptors (mGluRs ...

The metabotropic glutamate receptors ... we investigated whether these receptors modulate nociceptive signaling, and found that agonist-induced activation of peripheral group I mGluRs leads ...

A new study in Engineering explores the role of astrocytic G protein-coupled receptors in drug addiction. It shows that these receptors, including ...

and metabotropic glutamate receptor 5 (mGLUR5). These receptors respond to various ligands, modulating astrocytic signaling ...