Researchers from Charité - Universitätsmedizin Berlin and the Max Delbrück Center have identified the precise mechanism by ...

Microglia, the brain's immune cells, usually serve as diligent guardians. They eliminate intruders such as microbes and clear away cellular debris—including the plaques typical of Alzheimer's disease.

A new study reveals that IL-12, an inflammatory molecule, accelerates Alzheimer’s disease by damaging brain cells and preventing plaque clearance. Blocking IL-12 in mice halted disease-related changes ...

Researchers found that accelerating the brain's waste removal system could have tremendous implications for our memory.

indicating that microglia may contribute to age-related neurodegenerative diseases. Since aging perturbs myelin structure, and myelin degenerates in Alzheimer’s disease, we next wondered whether the ...

When lymphatic drainage was disrupted, the burden shifted to microglia, the brain’s resident immune cells ... restoring key brain communication functions that had been degraded in aging mice. These ...