Mitochondria and mitochondrial autophagy play a vital role in cellular health and failure of these pathways can have a devastating effect on cellular homeostasis.

Autophagy is the process by which cells digest and renew their internal structures, recycling damaged or malfunctioning proteins and organelles. By reusing these basic molecules, the cell gains ...

The paper: H. Zhang, et al., “Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia,” J Biol Chem, 283:10892–903, 2008. (Cited in 72 papers) The finding: By examining ...

A Dundee academic has been awarded a prestigious national prize for his work on neurodegenerative diseases, including ...

Feb. 13, 2025 — A new study unravels the relationship between mitofusins (mitochondrial proteins) and autophagy. Using gene editing with CRISPR-Cas9, the team has been able to study these ...

After a year teaching an algorithm to differentiate between the echolocation calls of different bat species, Katarina decided she was simply too greedy to focus on one field. Following an internship ...

This review highlights the growing interest in ginsenosides, especially Compound K (CK), as potential anti-aging agents due ...

We are driven to understand the signals regulating tissue-specific autophagy signalling in mammalian health and disease. Understanding the physiological regulation and significance of selective ...