Scientists at EMBL have captured how human chromosomes fold into their signature rod shape during cell division, using a ...

With a few exceptions, eukaryotic chromosomes have a single centromere that ensures their accurate segregation during mitosis. Chromosomes that lack centromeres segregate randomly during mitosis ...

The five phases of mitosis and cell division tightly coordinate the movements of hundreds of proteins. How did early biologists unravel this complex dance of chromosomes? The most obvious ...

The scientists built a computational model that allowed them to simulate the process of chromosome compaction based on a few fundamental assumptions ...

Same as in mitosis, except that the spindle fibers from each centriole attach to one chromosome of a matching chromosome pair. In other words, the fibers from one centriole attach to 23 ...

In eukaryotes, segregation of duplicated chromosomes is performed by the mitotic spindle, a cellular machine composed of microtubules and their associated proteins. Spindles are built from ...

Cell division is essential to the propagation of life. During cell division, mitotic spindles segregate duplicated chromosomes with high fidelity. Spindle structure depends on the proper polar ...

have shaped the evolution of chromosomes and contributed to the diversity of life on Earth. Mitosis is the process by which a cell duplicates its chromosomes and divides into two identical daughter ...

The daughter cells are genetically identical because they each contain the same diploid chromosome complement as the original parent cell. It can be seen in the stages shown above that mitosis ...

HIV-1 Vif induces a unique and prolonged pseudo-metaphase arrest by disrupting phosphatase feedback regulation at the kinetochore.

The centrioles begin to separate. The activities are the same as in mitosis, except that in this cell the chromosomes attach to the membrane of the nucleus and then pair up with their ...