The TP53 gene is a gene that is mutated in many cancers. It is the most common gene mutation found in cancer cells. A tumor-suppressor gene, TP53 codes for a protein that inhibits the development ...

Spatially resolved protein profiling in pancreatic adenosquamous carcinoma. Age, number of genomic alterations (GA) per tumor, and alteration frequency of select commonly altered genes based on TP53 ...

A study released by the National Cancer Center Japan has revealed higher rates of mutations in a tumor-suppressing gene, TP53, in Japanese cancer patients compared to those in the United States ...

Lung cancer cases are increasing in people who have never smoked, especially in women, a new study by the World Health Organization's cancer agency ...

Instead, our data suggest that a mutation in SOCS1 detectable after infusion may have cooperated with CAR activity, CAR vector integration in TP53, or both to contribute to the development of CAR+ ...

In January 2025, Aptose announced the initiation of the TUSCANY trial and dosing in the first cohort of newly-diagnosed AML patients with the lowest starting dose (40 mg) of TUS as part of the ...