Mothers of babies with NLE rarely have skin lesions like those seen in their infants, nor do they get heart block. A guinea pig model in which sera from NLE mothers was injected, showed deposition ...

Background A 23-year-old white woman with a 3-year history of systemic lupus erythematosus and a 15-month ... and a palpable nonblanching purpuric rash over both forearms and both legs.

However, symptoms often overlap with those of systemic lupus erythematosus (SLE). These include: muscle and joint pain sometimes with swelling flu-like symptoms of fatigue and fever serositis ...

for example discoid lupus erythematosus (DLE). Caproni and colleagues, therefore, studied the expression of CD40 and CD40L in skin lesions of patients with SCLE. The authors conclude that the CD40 ...

“In addition to decreasing the inflammation by decreasing lesional staphylococcus aureus, the mupirocin treatment also lowered skin monocyte levels, which are important in driving cutaneous lupus,” ...

The treatment for the cutaneous lesions is strict sun avoidance and mid to low-potency topical steroids. Systemic steroids are not required for managing cutaneous lesions. Systemic antimalarial ...