It's believed that over 20 million Americans suffer from some form of damage to their nerves, or neuropathy. For the afflicted, pain, tingling or numbness often begins in the hands or feet.

There are many medical conditions that can cause nerve pain in the legs and feet, including chronic ones like multiple sclerosis (MS). There are several different ways that MS can cause nerve pain.

Sciatic nerve pain (also called sciatica or lumbar radiculopathy) affects your lower back and can radiate to the thighs and legs. The pain occurs due to compression at the root of the sciatic ...