Hemoglobin has played a central role in the understanding of many biochemical and biophysical principles, as Eaton and colleagues point out on page 351 of this issue of Nature Structural Biology.

Cord blood electrophoresis normally reveals high ... Of the tested infants, 21 had Hb F as the sole detectable hemoglobin. These included 14(66%) preterm infants. Cesarian section was performed ...

Alkaline hemoglobin electrophoresis on cellulose acetate is commonly used to identify major hemoglobin variants with acidic pH electrophoresis on citrate agar often utilized as an auxiliary step ...