One reason cancer is so difficult to eradicate is its metabolic flexibility, she said. Her findings suggest that the salvage pathway could be an access route for cancer cells to get their nucleotide ...

A team led by Prof. Wuran Wei from West China Hospital of Sichuan University and Dr. Dechao Feng from the Division of Surgery ...

This pathway is energy-intensive and requires multiple enzymatic ... One of the main challenges is the complexity of nucleotide metabolism and its regulation. The intricate networks of enzymes and ...