Researchers have developed eye drops that extend vision in animal models of a group of inherited diseases that lead to ...

Researchers at the National Institutes of Health (NIH) have developed eye drops that extend vision in animal models of a ...

Advances in mass spectroscopy using the 'top-down' approach to proteomics, in which intact proteins are ionized directly without previous peptide fragmentation, are proving especially fruitful for ...

explains Dr. Ritterhoff. This short protein fragment, a so-called peptide, can be produced synthetically and directly applied intravenously as a drug with immediate therapeutic efficacy.

Named after shotgun DNA sequencing, in which long DNA sequences are computationally reconstructed from many short sequencing reads, shotgun proteomics identifies proteins from tandem mass spectra ...

However, the peptide must reverse its twist to relieve the torsional strain and by doing so disrupts the tau fibril, enabling its fragmentation. We are currently characterizing the fragments produced ...

AIP on timsTOF Ultra 2: Significantly improved peptide and protein identification ... top-down MS/MS protein spectra from any kind of fragmentation method." Professor Francisco Alberto Fernandez ...

peptide mapping remains a critical workflow in determining and monitoring post-translational modifications and other quality attributes. Zhengwei Chen, Senior Applications Scientist, will demonstrate ...