Frizzled (Fz)/planar cell polarity (PCP) signalling is a conserved mechanism regulating the polarity of cells along the axes of a tissue. Fz/PCP regulates a diverse array of processes including ...

Cilia drive fluid flow in development and physiology, but this requires that all cilia in a tissue orient the same way. Earlier studies indicated that both planar cell polarity (PCP) signalling ...

Scientists have uncovered a key mechanism in jellyfish embryos that provides new insights into how the body plan of these animals develops along a central axis from their "head" to "tail.

We are interested in the genetic control of animal development and how cells interact to build complex tissues and organs. We focus on the particular problem of how cells coordinate their polarity ...

I am interested in uncovering novel components of the mechanisms that drive morphogenesis during development. In particular, I hope to link what is currently known concerning global patterning systems ...