When skin is cut or damaged, tiny cell fragments circulating in the blood, called platelets, arrive at the injury and spread out to stop the blood from leaking out. Once enough layers of platelets ...

IPA: Inhibition of platelet aggregation; iv.: Intravenous. The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or ...

Reduction in the production of this potent platelet agonist can significantly reduce platelet aggregation. However, despite all the shortcomings, aspirin remains the cornerstone of antiplatelet ...

Dr. Woulfe's research interests focus primarily on the intracellular signaling mechanisms of platelet activation and how signaling in platelets contributes to thrombosis in vivo. Agonists that extend ...

It will be important to establish whether the use of TPO-R agonists in combination with agents that minimize platelet removal, such as the monoclonal antibody to CD20, rituximab, will provide ...