Activation of platelets is triggered by direct adhesion of the parasites to platelet receptors, in addition to other stimuli, such as increased levels of CRP. After contact with parasites ...

Megakaryocytes (MKs), known for their role in platelet production ... The review emphasizes the expression of immune receptors by MKs, such as toll-like receptors (TLRs), Fc gamma receptors ...

Founded in 2017, Cell Receptor is collaborating with universities to extend knowledge and research in this area. Actively growing tumor cells have platelet receptors on their surface. These ...

Brain tumours remain the most common cause of death from childhood cancer. Paediatric high-grade gliomas (pHGG) in particular are a mostly fatal disease group with a median survival time of less than ...

Further analysis of mouse platelets also suggested that IPA acts on a specific platelet component called the pregnane X receptor to have its effect on platelet activation. Findings from human and ...

This inhibition results in an increase in local concentrations of adenosine which acts on the platelet A2-receptor thereby stimulating platelet adenylate cyclase and increasing platelet cyclic-3 ...

the present study reported a novel role of gut microbiota-derived IPA in modulating platelet activation by binding to the pregnane X receptor (PXR), thereby decreasing the phosphorylation of Src ...

These unique receptors translate mechanical stimuli into ... Their roles extend from modulating platelet aggregation and ...

the present study reported a novel role of gut microbiota-derived IPA in modulating platelet activation by binding to the pregnane X receptor (PXR), thereby decreasing the phosphorylation of Src ...

Platelets have a broad repertoire of receptor molecules that enable them to sense invading pathogens and infection-induced inflammation. Consequently, platelets exert antimicrobial effector ...