Activation of platelets is triggered by direct adhesion of the parasites to platelet receptors, in addition to other stimuli, such as increased levels of CRP. After contact with parasites ...

Megakaryocytes (MKs), known for their role in platelet production ... The review emphasizes the expression of immune receptors by MKs, such as toll-like receptors (TLRs), Fc gamma receptors ...

Founded in 2017, Cell Receptor is collaborating with universities to extend knowledge and research in this area. Actively growing tumor cells have platelet receptors on their surface. These ...

When skin is cut or damaged, tiny cell fragments circulating in the blood, called platelets, arrive at the injury and spread out to stop the blood from leaking out. Once enough layers of platelets ...

It has been previously shown that the nuclear receptor subfamily 4 group A (NR4A) plays an important role in cardiovascular ...

Pediatric high-grade gliomas, particularly H3K27M diffuse midline gliomas (DMG), are aggressive malignant brain tumors with a poor prognosis.

This inhibition results in an increase in local concentrations of adenosine which acts on the platelet A2-receptor thereby stimulating platelet adenylate cyclase and increasing platelet cyclic-3 ...

the present study reported a novel role of gut microbiota-derived IPA in modulating platelet activation by binding to the pregnane X receptor (PXR), thereby decreasing the phosphorylation of Src ...

Platelets have a broad repertoire of receptor molecules that enable them to sense invading pathogens and infection-induced inflammation. Consequently, platelets exert antimicrobial effector ...